1/3 of all couples with infertility suffers from what we as doctors call unexplained infertility. This is due to the fact, that although the patients have been through all kinds of diagnostic procedures, no pathology has been found.

Unexplained infertile couples have very good results following fertility treatment although we do not know the couse for the infertility.

Normally the treatment is initially intrauterine insemination and if this is not suscessfull IVF treatment.

Treatment with hormones assists the egg in its phase of maturation, whereas the insemination secures that the sperm cells are added to the egg exactly at the time of the ovulation. This can be an advantage, as we assume that unexplained infertility is caused by:

• The woman’s eggs have troubles disengaging from the ovaries
• The sperm cells do not survive very long in the uterine tubes
• The woman might produce an antidote, which kills the sperm cells on their way to the uterus
• Endometriosis (possible the cause in 80% of the cases)

• Insemination (IUI)
• In Vitro Fertilisation (IVF)

More than 65% of the patients suffering from unexplained infertility conceive during the treatment.